Відео

So… vampires are real? And rich

For those wanting more on the "SO WHAT" of Sucralose, see this Tweet covering 2020 data from Cell Metabolism: x.com/nicknorwitz/status/1807018727482737120

I have lost 55 lbs and reversed a heart blockage on low carb. I refused statins because they would reduce my exercise level. Refusing medical advice is dangerous but it must come with self discipline and a lot of research.

I did not catch why we need to care that our bodies know the difference?

Amazing teaching material, which I will refer to over and over - thank you! Could you please do a separate vid on benefits / negative side effects of sucralose alone? I'm requesting this because of two reasons: 1. It's the most widely used sweetener in protein powder supplements 2. There is no true evidence-based science research education out there, that I can find regarding this particular niche Thanks, and love

Who in the hell wants to live forever?

There is a study that says sucralose disturbs dna, and can cause cancer.

Yes, I did enjoy the explanation but it also brought more questions of other non-nutritive sweeteners such as monk fruit, stevia, erythritol, allulose, & many others.

ADA's financial relationship with SPLENDA is currently a source of much 'discussion'

They want to put lights in our bellies???

Have an International Heart Association to compete with American Heart Association

Hey Dr. Norwitz, my favorite moderate exercise is jogging, great evaluation by the way Thanks : )

I get how fructose inhibits the production of fat burning enzymes. However, you then stated that fructose increases insulin resistance. What is the mechanism of this?

Interestingly I eat three times a day, sometimes later at night and have no difficulty sleeping and am unable to gain weight.

Very good video. I wish social media creators would emphasize more on exercise rather than nutrition and diet. It is cardio and strength training that prevent sarcopenia, osteoporosis and other aging issues. Diet is useless on its own

Sorry, what Trump said about abortion is not stupid, there are women aborting (killing) their babies right before birth.😢

I'm a Monkfruitian who has vacationed in Stevia Land. It wasn't a bad time, but I'm keen on visiting Allulosia next. I hear their GLP1 temples are beautiful enough to turn a tourist into a citizen.

I've actually noticed not feeling as driven to overeat after artificial sweeteners, though I thought I was reacting to my stable blood sugar rather than a gut signal. I don't see how this is a bad thing. If anything, sweetness that doesn't drive overeating is better than free.

If the brain can figure out the difference between real sugar and fake sugars , so should not be producing the insulin spikes for fake sugars as everyone is claiming… personally I mix keto with three day fasts and guzzle monster ultra watermelon or kiwi all day long… doesn’t keep me from hitting 3.6 on my ketones… I don’t think I could do that if I was spiking my insulin levels…

So do SGLT 1 inhibitors reduce learned sucrose seeking? For example, “Dual SGLT1/s Inhibitors: Sotagliflozin (Inpefa) is a dual SGLT1/2 inhibitor approved by the FDA to reduce the risk of cardiovascular mortality and hospitalization for heart failure in adults with T2DM, chronic kidney disease, and other cardiovascular risk factors (Facts and Comparisons, 2024a). Sotagliflozin had… been studied as an adjunctive therapy in T1DM. While phase III trials showed an improvement in A1C tests after 24 weeks, the rate of DKA was higher in the sotagliflozin group compared to placebo and therefore is not recommended as a treatment for T1DM (Weinstock, 2024).” From: SGLT2 and SGLT1: What's the Difference? Nov 26 2018 by Myrna B. Schnur, MSN, RN

I have high insulin. Sucrose and glucose stimulate release of insulin. I also believe that certain zero-calorie sweeteners also stimulate release of excess insulin. Does this research inform us as to which other sweeteners do or do not stimulate insulin release? I want to avoid anything that releases extra insulin -- so is that all sweeteners, or only sweeteners that behave a certain way under Dr. Bohorquez's research?

hmmm ... so enabling an existing addiction is what it does

Another great video with data from a study I haven't heard of before. Great job again Dr. Norwitz!

Now I know the reason for alien anal sondes ......

Nos, Strix, resurgemus.

Super cool technique! This got me wondering if the speed with which ingested sweet molecules show up in the duodenum, and/or the length of time they stick around, plays a role in preference. Quick arrival in the duodenum seems like it would reinforce sweet-seeking behavior, since the link between taste on tongue and response in body would be very clear. I wonder if lingering in the duodenum would either confuse the body’s ability to make clear associations, or lead to receptor downregulation? There’s a paper that looks at gastric emptying rate and small bowel water retention rate for water vs grapefruit juice vs glucose solution vs fructose solution. The rates seem to differ in different ways depending on the source of the sweetness. Anyway, thanks for bringing this research to us and enlivening it with your communication skills!

I wonder if long term consumption of a sweetner in the absence is of carbs can pavlovian train the body to not react at the empty signal? It seems to me like a dog that its whole life had a bell ring before food later reacting to only the bell sound with out any calories

I admire your dedication and enthusiasm, but what I (and probably everyone in the universe) want to know is whether artificial sweeteners make you fat and inflamed or not. Eleven and a half minutes of meaningless word sallad for us dummies...

Really interesting, thanks. I personally choose stevia, even it makes me binge sometimes. I don't really care much about it, because i binge on low calorie food. I always thought it's just the sweet taste. Does similiar data exist for stevia? Maybe other molecules don't trigger a neuropod respone.

it is absolutly possibly o distnguish between all the sweeteners on the tongue, perhaps just not everyone ...when taking them pure. food industry must carefuly blend other stuff to hide that difference.

Us usual, you are an amazing educator.

I usually consume stevia and zero soda. Once I took a normal soda with sugar then I had a headache. I suppose you are wrong, I think our body doesn't know the difference. If I consume only sugar, my body will spike insulin, but if I only consume sweeteners and occasionally consume too much sugar, my body won't take the measures unaware of the danger

What about Stevia?

Splenda and sucralose are not the same thing; Splenda is at least half maltodextrin (it is the first ingredient listed on the bag), which is higher on the glycemic index than sugar. Splenda has spent so much money with the diabetes association and done such an amazing job with marketing that everyone uses the terms interchangeably, including scientist and researchers. This makes it difficult for me to trust any research or products using sucralose. I'll typically avoid sucralose in most products for that reason, unless products that I trust specifically state that they DON'T use Splenda.

If they used Splenda it’s more maltodextrin than sucralose in powdered form. (Splenda contains maltodextrin, a digestible sweetener that's usually combined with 95% dextrose (D-glucose) and a small amount of sucralose. Maltodextrin and dextrose are carbohydrates that contribute to Splenda's calorie content of 3.36 calories per gram. )

Dr Bernstein states that sucralose is safe as long as it doesn’t have dextrose or maltodextrin. I found it and use it. No spike.

1:15 Nooo! Bring the cute mouse back! 1:22 Phew thanks!

Sucralose probably also has a negative effect on the mucin layer of the intestine promoting leaky gut and chronic inflammation.

Great content

Interesting... now for your next assignment, explain how Allulose works and why it is so different and even beneficial. Just curious...

Excellent video! Sugar is highly addictive, so getting yourself detox from it, it takes up to three months, but it's so worth it. I no longer crave sweets anymore, my skin cleared up, my gums and teeth improved a lot. and I lost 10 lbs for just quitting sugar.

Fake sweeteners taste gross. Eat the real thing or better yet, don't! 😅

When people start saying that eating sweeteners increases insulin secretion just do this. Get a dozen sweetener tablets, put them in a pint of water and drink it. See what happens. I'll tell you..... nothing. You compare that to what happens if you had 12 spoonfuls of sugar. Donesn't it enter anyone's head that if you had such a insulin response to sweeteners without the glucose going into your system, you would have a hypoglycaemic crisis!!! Total rubbish

Speaking of curiosity, how to they shine light into the intestinal cavity and target the desired receptors?

So for allulose you can have your cake and eat it too? But not other artificial sweeteners?

allulose???????????i have been reading that allulose has other benefits other than just not adding sugar to the diet. is it also helping in the gut with the breakdown of carbs?

I feel like the dosage of sucralose is very high for what would be consumed considering its hundreds of times sweeter than sucrose. I'll dig into their methods and references.

I like my morning milk Matcha with some sweetner! I do not think I will give that up anytime soon xD My keto diet is, as a whole, healthy, so...

Loved this. I think I understood some of the possibilities this could offer, both in good and bad🤔

Here we go!! Expanding the brain!! Thanks Nick!